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media-gfx/ufraw

RAW Image format viewer and GIMP plugin

dev-libs/memkind

user extensible heap manager built on top of jemalloc

sci-biology/ntCard

Estimate k-mer coverage histogram of genomics data

sci-biology/idba

De novo De Bruijn graph assembler iteratively using multimple k-mers

sci-biology/megahit

Metagenome assembler using succinct de Bruijn graph approach with CUDA

sci-biology/vcflib

VCF/BED utils, Genotype Phenotype Association Toolkit (GPAT++)

sci-chemistry/gamess

A powerful quantum chemistry package

sci-chemistry/erkale

Quantum chemistry program for atoms and molecules

sci-libs/ensmallen

header only C++ library for numerical optimization

sci-libs/torchaudio

Data manipulation and transformation for audio signal processing

sci-physics/openmx

Material eXplorer

media-gfx/realsr-ncnn-vulkan

RealSR super resolution implemented with ncnn library

media-gfx/srmd-ncnn-vulkan

SRMD super resolution implemented with ncnn library

games-fps/gzdoom

A modder-friendly OpenGL source port based on the DOOM engine

sci-libs/calculix-ccx

A Free Software Three-Dimensional Structural Finite Element Program

media-gfx/gmic

GREYC's Magic Image Converter

sci-misc/ik_llama-cpp

llama.cpp fork with additional SOTA quants and improved performance

sci-misc/stable-diffusion-cpp

Diffusion model(SD,Flux,Wan,Qwen Image,Z-Image,...) inference in pure C/C++

sci-visualization/gwyddion3

Framework for Scanning Mode Microscopy data analysis (3.x unstable)

sci-libs/paru

parallel multifrontal LU factorization algorithms.

sci-ml/caffe2-cuda

A deep learning framework (CUDA backend)

sci-ml/caffe2-rocm

A deep learning framework (ROCm backend)

sci-ml/ik_llama-cpp

llama.cpp fork with additional SOTA quants and improved performance

dev-python/simsimd

Fastest SIMD-Accelerated Vector Similarity Functions for x86 and Arm

sci-libs/elpa

The publicly available ELPA library provides highly efficient and highly scalable direct eigensolvers for symmetric matrices

sci-physics/abinit

A software suite to calculate the optical, mechanical, vibrational, and other observable properties of materials

sci-physics/gpaw

GPAW is a density-functional theory (DFT) Python code based on the projector-augmented wave (PAW) method and the atomic simulation environment (ASE)

sci-physics/quantum-espresso

Suite for first-principles electronic-structure calculations and materials modeling

sci-libs/rocALUTION

Sparse iterative solvers and preconditioners on the ROCm platform

sci-misc/prism-llama-cpp

PrismML llama.cpp fork with Bonsai low-bit model support

sci-misc/kvmem-llama-cpp

CUDA llama.cpp runtime with tiered KV memory for long contexts

localai-backend/acestep-cpp

LocalAI music-generation backend (acestep.cpp gRPC server)

localai-backend/bonsai

LocalAI text-generation backend for 1-bit/ternary models (Bonsai fork of llama.cpp)

localai-backend/ced

LocalAI audio-event-detection backend (ced.cpp gRPC server)

localai-backend/crispasr

LocalAI speech backend (CrispASR gRPC server)

localai-backend/depth-anything

LocalAI depth-estimation backend (depth-anything.cpp gRPC server)

localai-backend/face-detect

LocalAI face-detection backend (face-detect.cpp gRPC server)

localai-backend/ik-llama-cpp

LocalAI text-generation backend (ik_llama.cpp gRPC server)

localai-backend/kimodocpp

LocalAI skeleton-animation backend (kimodo.cpp gRPC server)

localai-backend/llama-cpp

LocalAI text-generation backend (llama.cpp gRPC server)

localai-backend/locate-anything-cpp

LocalAI open-vocabulary detection backend (locate-anything.cpp gRPC server)

localai-backend/localvqe

LocalAI voice-quality-enhancement backend (LocalVQE gRPC server)

localai-backend/parakeet-cpp

LocalAI speech-to-text backend (parakeet.cpp gRPC server)

localai-backend/qwen3-tts-cpp

LocalAI text-to-speech backend (qwentts.cpp gRPC server)

localai-backend/rfdetr-cpp

LocalAI object-detection backend (rf-detr.cpp gRPC server)

localai-backend/sam3-cpp

LocalAI image-segmentation backend (sam3.cpp gRPC server)

localai-backend/stablediffusion-ggml

LocalAI image-generation backend (stable-diffusion.cpp gRPC server)

localai-backend/trellis2cpp

LocalAI 3D-generation backend (trellis2cpp gRPC server)

localai-backend/vibevoice-cpp

LocalAI text-to-speech backend (vibevoice.cpp gRPC server)

localai-backend/whisper

LocalAI speech-to-text backend (whisper.cpp gRPC server)