Browse sci-biology
aaindex
Amino acid indices and similarity matrices
abyss
Assembly By Short Sequences - a de novo, parallel, paired-end sequence assembler
allpaths
De novo assembly of whole-genome shotgun microreads
amos
A Modular, Open-Source whole genome assembler
arb
Tools for DNA/RNA sequence database handling and data analysis, phylogenetic analysis
ariadne
Protein sequences and profiles comparison
augustus
Eukaryotic gene predictor
autoprime
A command line tool to generate primers for RT-PCR
autoprimeweb
A web frontend for AutoPrime
beast-mcmc
Bayesian MCMC of Evolution & Phylogenetics using Molecular Sequences
bfast
Blat-like Fast Accurate Search Tool
biogrep
Biogrep matchs large sets of patterns against biosequence dbs and is optimized for multithreading.
bioperl
Perl tools for bioinformatics - Core modules
bioperl-db
Perl tools for bioinformatics - Perl API that accesses the BioSQL schema
bioperl-network
Perl tools for bioinformatics - Analysis of protein-protein interaction networks
bioperl-run
Perl tools for bioinformatics - Analysis run modules
biopython
Biopython - Python modules for computational molecular biology
bioruby
An integrated environment for bioinformatics using the Ruby language
biosql
A generic bioinformatics relational database model
biskit
A Python platform for structural bioinformatics
blat
The BLAST-Like Alignment Tool, a fast genomic sequence aligner
blossoc
A linkage disequilibrium association mapping tool
bowtie
An ultrafast memory-efficient short read aligner
bwa
Burrows-Wheeler Alignment Tool, a fast short genomic sequence aligner
ce
3-D protein structure comparison and alignment using the Combinatorial Extension (CE) method
clover
Cis-eLement OVERrepresentation: Detection of functional DNA motifs
clustalw
General purpose multiple alignment program for DNA and proteins
clustalw-mpi
A parallel (MPI) implemention of the Clustal-W general purpose multiple alignment algorithm
clustalx
Graphical interface for the ClustalW multiple alignment program
cluster
Clustering software for microarray analysis
codonw
Multivariate statistical analysis of codon and amino acid usage
consed
Consed: a genome sequence finishing program
cutg
Codon usage tables calculated from GenBank
dawg
DNA Assembly With Gaps: Phylogenetic aligner for sequence evolution simulation
dialign-tx
Greedy and progressive approaches for segment-based multiple sequence alignment
diya
Do It Yourself Annotation, a collection of tools and libraries for sequence assembly and annotation
elph
Estimated Locations of Pattern Hits - Motif finder program
embassy
A meta-package for installing all EMBASSY packages (EMBOSS add-ons)
embassy-cbstools
EMBOSS wrappers for applications from the CBS group
embassy-domainatrix
Protein domain analysis add-on package for EMBOSS
embassy-domalign
Protein domain alignment add-on package for EMBOSS
embassy-domsearch
Protein domain search add-on package for EMBOSS
embassy-emnu
EMBOSS Menu is Not UNIX - Simple menu of EMBOSS applications
embassy-esim4
EMBOSS integrated version of sim4 - Alignment of cDNA and genomic DNA
embassy-hmmer
EMBOSS wrappers for HMMER - Biological sequence analysis with profile HMMs
embassy-iprscan
InterProScan motif detection add-on package for EMBOSS
embassy-memenew
EMBOSS wrappers for MEME - Multiple Em for Motif Elicitation
embassy-mira
Fragment assembly add-on package for EMBOSS
embassy-mse
EMBOSS integrated version of MSE - Multiple Sequence Screen Editor
embassy-phylipnew
EMBOSS integrated version of PHYLIP - The Phylogeny Inference Package
embassy-signature
Protein signature add-on package for EMBOSS
embassy-structure
Protein structure add-on package for EMBOSS
embassy-topo
EMBOSS integrated version of TOPO - Transmembrane protein display
embassy-vienna
EMBOSS integrated version of the Vienna RNA package - RNA folding
emboss
The European Molecular Biology Open Software Suite - A sequence analysis package
ensembl-perl
Additional perl modules for bioperl that can be used to easily access the EnsEMBL database
ensembl-perl-compara
Additional perl modules for bioperl that can be used to easily access the EnsEMBL database
erpin
Easy RNA Profile IdentificatioN, an RNA motif search program
eugene
Eukaryotic gene predictor
exonerate
exonerate is a generic tool for pairwise sequence comparison
fahmon
wxGTK monitor for the folding@home client
fasta
FASTA is a DNA and Protein sequence alignment software package
fastdnaml
Maximum likelihood phylogenetic tree builder for DNA sequences
fasttree
Fast inference of approximately-maximum-likelihood phylogenetic trees
finchtv
A cross-platform graphical viewer for chromatogram files.
foldingathome
Folding@Home is a distributed computing project for protein folding.
foldx-bin
A force field for energy calculations in proteins
gbrowse
The generic genome browser provides a display of genomic annotations on interactive web pages
genepop
Population genetics analysis
generecon
Generecon performs linkage disequilibrium gene mapping based on coalescent theory using Bayesian Markov Chain Monte Carlo methods.
gibbs
The Gibbs Motif Sampler identifies motifs, conserved regions, in DNA or protein sequences
glimmer
An HMM-based microbial gene finding system from TIGR
glimmerhmm
An eukaryotic gene finding system from TIGR
gmap
A Genomic Mapping and Alignment Program for mRNA and EST Sequences
gnaural
A programmable binaural-beat generator, implementing the principle of binaural beats as described in the October 1973 Scientific American article "Auditory Beats in the Brain" (Gerald Oster).
grappa
Genome Rearrangements Analysis under Parsimony and other Phylogenetic Algorithms
hmmer
Sequence analysis using profile hidden Markov models
infernal
Inference of RNA alignments
iqpnni
Important Quartet Puzzling and NNI Operation
jalview
A multiple DNA sequence alignment editor
jtreeview
Java TreeView renders gene expression data into several interactive views.
kalign
Global and progressive multiple sequence alignment
lagan
LAGAN, Multi-LAGAN, Shuffle-LAGAN, Supermap: Whole-genome multiple alignment of genomic DNA
last
Genome-scale comparison of biological sequences
mafft
Multiple sequence alignments using a variety of algorithms
mammoth
MAtching Molecular Models Obtained from THeory
maq
Mapping and Assembly with Qualities - mapping Solexa and SOLiD reads to reference sequences
maqview
GUI for sci-biology/maq, a short read mapping assembler
mauve
Multiple genome alignment with large-scale evolutionary events (GUI component)
mauvealigner
Multiple genome alignment with large-scale evolutionary events (aligner component)
mavid
Multiple alignment of large DNA sequences
meme
The MEME/MAST system - Motif discovery and search
merlin
Statistical analysis of gene flow in pedigrees
mira
Whole Genome Shotgun and EST Sequence Assembler for Sanger, 454 and Solexa / Illumina
miranda
An algorithm for finding genomic targets for microRNAs
mmult
MAtching Molecular Models Obtained from THeory
mosaik
A reference-guided aligner for next-generation sequencing technologies
mothur
A suite of algorithms for ecological bioinformatics
mpiblast
An MPI implementation of NCBI BLAST
mrbayes
Bayesian Inference of Phylogeny
mreps
Identification of serial/tandem repeats in DNA sequences
mummer
A rapid whole genome aligner
muscle
Multiple sequence comparison by log-expectation
ncbi-tools
Development toolkit and applications for computational biology, including NCBI BLAST
ncbi-tools++
NCBI C++ Toolkit, including NCBI BLAST+
newbler
Roche 454 pyrosequencing assembler
njplot
A phylogenetic tree drawing program which supports tree rooting
pals
Pairwise Aligner for Long Sequences
paml
Phylogenetic Analysis by Maximum Likelihood
perlprimer
GUI application written in Perl to design primers for standard PCR, bisulphite PCR and Real-time PCR
phrap
Phrap, swat, cross_match: Shotgun assembly and alignment utilities
phred
A base caller for Sanger DNA sequencing
phylip
PHYLIP - The PHYLogeny Inference Package
phyml
Estimation of large phylogenies by maximum likelihood
piler
Analysis of repetitive DNA found in genome sequences
pilercr
Analysis of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs)
plink
Whole genome association analysis toolset
poa
Fast multiple sequence alignments using partial-order graphs
prank
Probabilistic Alignment Kit
primer3
Design primers for PCR reactions.
prints
A protein motif fingerprint database
probalign
Probalign uses partition function posterior probability estimates to compute maximum expected accuracy multiple sequence alignments
probcons
Probabilistic Consistency-based Multiple Alignment of Amino Acid Sequences
proda
Multiple alignment of protein sequences with repeated and shuffled elements
prosite
A protein families and domains database
psipred
Protein Secondary Structure Prediction
qrna
Prototype ncRNA genefinder
quicktree
Rapid reconstruction of phylogenies by the Neighbor-Joining method
raxml
A Program for Sequential, Parallel & Distributed Inference of Large Phylogenetic Trees
readseq
Reads and writes nucleic/protein sequences in various formats.
rebase
A restriction enzyme database
repbase
A database of repetetive genetic elements in various organisms.
repeatmasker
Screen DNA sequences for interspersed repeats and low complexity DNA
repeatmasker-libraries
A special version of RepBase used by RepeatMasker
rnaplex
RNA-RNA interaction search
rnaview
Generates 2D displays of RNA/DNA secondary structures with tertiary interactions
samtools
SAM (Sequence Alignment/Map), a format for storing large nucleotide sequence alignments
sap
Pairwise protein structure alignment via double dynamic programming
seaview
A graphical multiple sequence alignment editor
sequin
A tool to facilitate submission of data to the GenBank, EMBL, and DDBJ sequence databases
shrimp
SHort Read Mapping Package
sibsim4
A rewrite and improvement upon sim4, a DNA-mRNA aligner
signalp
Prediction of signal peptide cleavage sites in amino acid sequences
sim4
A program to align cDNA and genomic DNA
snpfile
A library and API for manipulating large SNP datasets
staden-bin
The Staden Package - Biological sequence handling and analysis
stride
A program for protein secondary structure assignment from atomic coordinates.
surfaceracer
Calculates exact accessible surface area, molecular surface area and average curvature of molecular surface for macromolecules
t-coffee
A multiple sequence alignment package
tgi-tools
The Gene Index Project utilities for genomic data processing: seqclean, cdbfasta, psx
tigr-assembler
A whole-genome shotgun assembler from TIGR
TMalign
Computer algorithm for protein structure alignment using dynamic programming and TM-score rotation matrix
tmhmm
Prediction of transmembrane helices in proteins
tophat
A fast splice junction mapper for RNA-Seq reads
transfac
A database of eucaryotic transcription factors
tree-puzzle
Maximum likelihood analysis for nucleotide, amino acid, and two-state data.
treeviewx
A phylogenetic tree viewer
trnascan-se
tRNA detection in large-scale genome sequences
twinscan
TwinScan, N-SCAN, and Pairagon: A gene structure prediction pipeline
ucsc-genome-browser
The UCSC genome browser suite, also known as Jim Kent's library and GoldenPath
vaal
A variant ascertainment algorithm that can be used to detect SNPs, indels, and other polymorphisms
velvet
A sequence assembler for very short reads
vienna-rna
The Vienna RNA Package - RNA secondary structure prediction and comparison
wgs-assembler
Whole-genome shotgun assembler based on the Celera Assembler
wise
Intelligent algorithms for DNA searches